The Role of Amniocentesis in the Diagnosis of Congenital Zika Syndrome

Jose Paulo Pereira; Melanie M Maykin; Zilton Vasconcelos; Elyzabeth Avvad-Portari; Andrea A Zin; Irena Tsui; Patricia Brasil; Karin Nielsen-Saines; Maria E Moreira; Stephanie L Gaw

doi:10.1093/cid/ciz013

The Role of Amniocentesis in the Diagnosis of Congenital Zika Syndrome

Clin Infect Dis. 2019 Aug 1;69(4):713-716. doi: 10.1093/cid/ciz013.

Affiliations

¹ Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira-Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
² Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco.
³ Jules Stein Eye Institute, Retina Division, University of California, Los Angeles.
⁴ Laboratorio de Doenças Febris Agudas, Instituto de Infectologia Evandro Chagas-Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
⁵ Division of Pediatric Infectious Diseases, Department of Pediatrics, University of California, Los Angeles.

Abstract

There are limited data on amniocentesis as a diagnostic tool for congenital Zika syndrome. Here we report on a prospective cohort of 16 women with suspected Zika virus infection in a highly endemic area, and discuss the role of amniocentesis in the prenatal diagnosis of fetal Zika infection.

Keywords: TORCH infection; ZIKV; perinatal infection; pregnancy; vertical transmission.

MeSH terms

Amniocentesis*
Female
Fetal Diseases / diagnosis*
Humans
Infectious Disease Transmission, Vertical
Pregnancy
Pregnancy Complications, Infectious / diagnosis*
Prospective Studies
Zika Virus Infection / congenital*
Zika Virus Infection / diagnosis*

The Role of Amniocentesis in the Diagnosis of Congenital Zika Syndrome

Authors

Affiliations

Abstract

MeSH terms

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