Performance of an immuno-rapid malaria Pf/Pv rapid diagnostic test for malaria diagnosis in the Western Brazilian Amazon

Rev Soc Bras Med Trop. 2019 Jan 17:52:e20170450. doi: 10.1590/0037-8682-0450-2017.

Abstract

Introduction: Rapid diagnostic tests (RDTs) for detecting Plasmodium antigens have become increasingly common worldwide. We aimed to evaluate the accuracy of the Immuno-Rapid Malaria Pf/Pv RDT in detecting Plasmodium vivax infection compared to standard thick blood smear (TBS) under microscopy.

Methods: Hundred and eighty-one febrile patients from the hospital's regular admissions were assessed using TBS and RDT in a blinded experiment.

Results: RDT showed a sensitivity of 98.9%, specificity of 100%, and accuracy of 99.5% for P. vivax infection when compared to TBS.

Conclusions: The RDT is highly accurate, making it a valuable diagnostic tool for P. vivax infection.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Antigens, Protozoan / immunology*
  • Brazil
  • Diagnostic Tests, Routine / methods*
  • Female
  • Humans
  • Malaria, Falciparum / diagnosis*
  • Malaria, Vivax / diagnosis*
  • Male
  • Plasmodium falciparum / immunology*
  • Plasmodium vivax / immunology*
  • Prospective Studies
  • Sensitivity and Specificity

Substances

  • Antigens, Protozoan