Toll-like receptor 4 promoter polymorphisms in a familial mediterranean fever patient with asymptomatic bacteriuria

Shinichiro Kawamoto; Ryota Masutani; Keiji Kurata; Etsuko Shima; Yoshinori Iwatani; Takayuki Takubo

doi:10.1002/ccr3.1941

Toll-like receptor 4 promoter polymorphisms in a familial mediterranean fever patient with asymptomatic bacteriuria

Clin Case Rep. 2018 Nov 25;7(1):155-159. doi: 10.1002/ccr3.1941. eCollection 2019 Jan.

Authors

Shinichiro Kawamoto¹, Ryota Masutani^{2

3}, Keiji Kurata⁴, Etsuko Shima⁵, Yoshinori Iwatani³, Takayuki Takubo⁶

Affiliations

¹ Department of Transfusion Medicine and Cell Therapy Kobe University Hospital Hyogo Japan.
² Department of Central Clinical Laboratory Osaka Medical College Hospital Osaka Japan.
³ Department of Biomedical Informatics, Division of Health Sciences Osaka University Graduate School of Medicine Osaka Japan.
⁴ Department of Medical Oncology/Hematology Kobe University Hospital Hyogo Japan.
⁵ Department of General Medicine Kobe Central Hospital Hyogo Japan.
⁶ Japanese Red Cross Society Osaka Japan.

Abstract

A periodic fever, due to inherited inflammatory disorders, can be misdiagnosed as a common infection, when a possible pathogen is detected from a patient. TLR4 SNPs that are responsible for asymptomatic bacteriuria might disturb the pathophysiology of familial Mediterranean fever without MEFV mutations.

Keywords: SNPs; TLR4; asymptomatic bacteriuria; familial Mediterranean fever; outer membrane vesicles.

Publication types

Case Reports