Late Identification of Chikungunya Virus in the Central Nervous System of a 2-Month-Old Infant: Persistence of Maternal-Neonatal Infection?

J Pediatric Infect Dis Soc. 2019 Sep 25;8(4):374-377. doi: 10.1093/jpids/piy135.

Abstract

We report here a probable case of vertical transmission of chikungunya infection with confirmed maternal viremia close to labor that led to severe infection in the newborn. The newborn progressed with cutaneous lesions and irritability 2 months after vertical transmission, when chikungunya virus was detected in the infant's CSF by a molecular diagnostic test (real-time polymerase chain reaction).

Keywords: chikungunya; neonatal encephalopathy; neonatal sepsis; newborn; vertical transmission.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Central Nervous System / virology*
  • Chikungunya Fever / cerebrospinal fluid*
  • Chikungunya Fever / diagnosis*
  • Chikungunya Fever / transmission
  • Chikungunya Fever / virology
  • Chikungunya virus / isolation & purification*
  • Female
  • Humans
  • Infant
  • Infectious Disease Transmission, Vertical*
  • Pregnancy
  • Pregnancy Complications, Infectious / virology
  • Viremia