Cluster-randomised trial of a nurse-led advance care planning session in patients with COPD and their loved ones

Thorax. 2019 Apr;74(4):328-336. doi: 10.1136/thoraxjnl-2018-211943. Epub 2019 Jan 19.

Abstract

Rationale: Advance care planning (ACP) is uncommon in patients with chronic obstructive pulmonary disease (COPD).

Objectives: To assess whether a nurse-led ACP-intervention can improve quality of patient-physician end-of-life care communication in patients with COPD. Furthermore, the influence of an ACP-intervention on symptoms of anxiety and depression in patients and loved ones was studied. Finally, quality of death and dying was assessed in patients who died during 2-year follow-up.

Methods: A multicentre cluster randomised-controlled trial in patients with advanced COPD was performed. The intervention group received an 1.5 hours structured nurse-led ACP-session. Outcomes were: quality of patient-physician end-of-life care communication, prevalence of ACP-discussions 6 months after baseline, symptoms of anxiety and depression in patients and loved ones and quality of death and dying.

Results: 165 patients were enrolled (89 intervention; 76 control). The improvement of quality of patient-physician end-of-life care communication was significantly higher in the intervention group compared with the control group (p<0.001). The ACP-intervention was significantly associated with the occurrence of an ACP-discussion with physicians within 6 months (p=0.003). At follow-up, symptoms of anxiety were significantly lower in loved ones in the intervention group compared with the control group (p=0.02). Symptoms of anxiety in patients and symptoms of depression in both patients and loved ones were comparable at follow-up (p>0.05). The quality of death and dying was comparable between both groups (p=0.17).

Conclusion: One nurse-led ACP-intervention session improves patient-physician end-of-life care communication without causing psychosocial distress in both patients and loved ones.

Keywords: palliative care.

Publication types

  • Multicenter Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Advance Care Planning / organization & administration*
  • Aged
  • Anxiety / etiology
  • Anxiety / prevention & control
  • Cluster Analysis
  • Death
  • Depression / etiology
  • Depression / prevention & control
  • Family / psychology*
  • Female
  • Health Communication
  • Humans
  • Male
  • Middle Aged
  • Netherlands
  • Physician-Patient Relations
  • Pulmonary Disease, Chronic Obstructive / nursing*
  • Pulmonary Disease, Chronic Obstructive / psychology
  • Quality of Health Care
  • Terminal Care / standards