Nipple leiomyoma: A rare neoplasm with a broad spectrum of histologic appearances

J Cutan Pathol. 2019 May;46(5):343-346. doi: 10.1111/cup.13423. Epub 2019 Feb 8.

Abstract

Cutaneous leiomyomas are rare benign smooth-muscle tumors. These lesions are distinguished based on their cell of origin and are subclassified as pilar leiomyoma, angioleiomyoma, and genital-type leiomyoma. Nipple leiomyoma is the least common genital-type leiomyoma, arising from the dartoic muscle cell of the nipple. Histologic examination of the lesion is necessary for definitive diagnosis, and these uncommon tumors can pose a diagnostic challenge. We describe herein a series of six nipple leiomyomas with a spectrum of histologic appearances.

Keywords: cutaneous leiomyoma; nipple leiomyoma; smooth-muscle tumors.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Angiomyoma* / metabolism
  • Angiomyoma* / pathology
  • Female
  • Humans
  • Infant
  • Male
  • Middle Aged
  • Nipples* / metabolism
  • Nipples* / pathology
  • Skin Neoplasms* / metabolism
  • Skin Neoplasms* / pathology