Successful in utero stem cell transplantation in X-linked severe combined immunodeficiency

Blood Adv. 2019 Feb 12;3(3):237-241. doi: 10.1182/bloodadvances.2018023176.

Abstract

  1. IUT enables rapid immune reconstitution and avoids many clinical and economic problems; however, the indication is still limited.

  2. IUT may be a treatment option in select cases, eg, fetuses exposed to a significant infectious risk, where a matched sibling donor exists.

Publication types

  • Case Reports

MeSH terms

  • Child, Preschool
  • Female
  • Hematopoietic Stem Cell Transplantation / methods*
  • Humans
  • Transplantation Conditioning / methods*
  • X-Linked Combined Immunodeficiency Diseases / pathology
  • X-Linked Combined Immunodeficiency Diseases / therapy*