Long-term adherence to ambulatory initiated continuous positive airway pressure in non-syndromic OSA children

Sleep Breath. 2019 Jun;23(2):575-578. doi: 10.1007/s11325-018-01775-2. Epub 2019 Jan 26.

Abstract

Purpose: In children, the usual indications for continuous positive airway pressure (CPAP) are residual OSA after adenotonsillectomy and/or persistent OSA due to obesity. Data concerning adherence (hours/night) following ambulatory CPAP initiation are scarce.

Methods: An observational cohort of 78 children was followed over 2 years. All exhibited sleep-disordered breathing (SDB) symptoms, were assessed by polysomnography, and prescribed CPAP. CPAP was initiated at hospital for 10 children.

Results: OSA children, mean age 10.4 ± 3.2 years, were mostly males (75.6%), with a mean body mass index of 21.2 ± 7.3 kg/m2, and mean apnea+hypopnea index of 12.2 ± 10.6 events/hour. Seventy-two children were still on CPAP at 3 months, 63 at 6 months, 55 at 1 year, and 34 at 2 years. CPAP was discontinued thanks to rehabilitation programs, dento-facial orthopedics, and/or weight loss. Mean CPAP adherence at 1, 3, 6, 12, and 24 months was respectively 6.1 ± 2.8, 6.2 ± 2.6, 6.2 ± 2.8, 6.3 ± 2.8, and 7.0 ± 2.7 h/night. There was a trend towards higher CPAP adherence and younger age, primary versus middle/high school attendance, higher baseline apnea+hypopnea index, and neurocognitive disorders.

Conclusion: In our population, mean CPAP adherence defined in hours per night was high and did not decrease during the 24-month follow-up. These findings support the feasibility of ambulatory CPAP initiation in non-syndromic OSA. The high CPAP adherence is expected to be associated with improvements in neurocognition, and in metabolic and cardiovascular parameters.

Keywords: Ambulatory; CPAP adherence; Children; OSA.

MeSH terms

  • Adolescent
  • Ambulatory Care / psychology*
  • Child
  • Child, Preschool
  • Cohort Studies
  • Continuous Positive Airway Pressure / psychology*
  • Female
  • Follow-Up Studies
  • Humans
  • Long-Term Care / psychology*
  • Male
  • Patient Compliance / psychology*
  • Polysomnography
  • Sleep Apnea, Obstructive / psychology*
  • Sleep Apnea, Obstructive / therapy*