Influence of the ethylene-related signal-inhibiting octapeptide NOP-1 on postharvest ripening and quality of 'Golden Delicious' apples

J Sci Food Agric. 2019 Jun;99(8):3903-3909. doi: 10.1002/jsfa.9613. Epub 2019 Feb 25.

Abstract

Background: Processes extending the shelf life of climacteric fruit play an important role in terms of a sustainable global food supply. In a previous study, a synthetic octapeptide (NOP-1) was shown to inhibit the interaction between ethylene receptor (ETR) and ethylene insensitive-2 (EIN2), and in consequence delay tomato ripening. We investigated for the first time the effect of NOP-1 on inhibiting the ripening of apples ('Golden Delicious') during postharvest.

Results: Using purified recombinant proteins from a bacterial expression system, we demonstrate here that EIN2 also interacts tightly (Kd = 136 ± 29 nmol L-1 ) with the corresponding apple ETR MdETR1. In line with previous binding studies on tomato ETRs, the ripening-delaying peptide NOP-1 clearly binds to the purified apple ETR. An NOP-1 solution (1000 µmol L-1 ) was applied with a brush or microdispenser and compared with apples treated with 1-methylcyclopropene (1-MCP) (SmartFresh™, Agrofresh) applied as gaseous treatment or untreated control fruits. NOP-1 inhibited colour development and chlorophyll degradation during shelf life. These effects were more pronounced with the brush application (surface film) than with microdroplets application (mimicking a sprayable formulation). NOP-1 did not alter ethylene release or respiration rate, whereas 1-MCP expectedly strongly suppressed both. There were no differences in quality parameters evaluated.

Conclusion: Our study shows that NOP-1 binds to MdETR1 which results in delaying of ethylene-dependent ripening developments of skin colour and chlorophyll. Besides application methods, possible reasons for the weak effect of NOP-1 in comparison with previous tomato experiments could be different receptor affinity and penetration differences. © 2019 Society of Chemical Industry.

Keywords: climacteric fruit; ethylene receptors; extend shelf life; peptide; quality changes.

MeSH terms

  • Cyclopropanes / pharmacology
  • Ethylenes / metabolism
  • Fruit / chemistry*
  • Fruit / drug effects
  • Fruit / growth & development*
  • Fruit / metabolism
  • Gene Expression Regulation, Plant / drug effects
  • Malus / drug effects*
  • Malus / genetics
  • Malus / growth & development
  • Malus / metabolism
  • Peptides / metabolism
  • Peptides / pharmacology*
  • Plant Growth Regulators / metabolism
  • Plant Growth Regulators / pharmacology*
  • Plant Proteins / genetics
  • Plant Proteins / metabolism
  • Receptors, Cell Surface / genetics
  • Receptors, Cell Surface / metabolism

Substances

  • Cyclopropanes
  • Ethylenes
  • Peptides
  • Plant Growth Regulators
  • Plant Proteins
  • Receptors, Cell Surface
  • ethylene receptors, plant
  • ethylene
  • 1-methylcyclopropene