The first experience of non-interferon therapy of HCV infection in patients with Wilson-Konovalov's disease

Ter Arkh. 2018 Nov 22;90(11):74-78. doi: 10.26442/terarkh2018901174-78.

Abstract

In the article we present three clinical observations demonstrating that HCV infection in patients with remission of Wilson disease causes an recrudescence of the disease, in one of the observations - decompensation of liver cirrhosis. In this study we first describe on the successful treatment of HCV infection with direct antiviral drugs in patients with Wilson disease. Establishment of all factors of liver damage and successful treatment (elimination of the virus, adequate lifelong medical treatment) allow to expect a favorable prognosis in patients with a combination of Wilson disease and HCV infection.

Keywords: HCV infection; Wilson–Konovalov’s disease; antiviral therapy; direct antiviral drug.; hepatitis C.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Antiviral Agents* / therapeutic use
  • Drug Therapy, Combination
  • Hepatitis C* / complications
  • Hepatitis C* / drug therapy
  • Hepatolenticular Degeneration* / complications
  • Humans
  • Liver Cirrhosis* / complications
  • Middle Aged

Substances

  • Antiviral Agents