In this Letter, a Tm3+-Ho3+ codoped tellurite glass microsphere laser in the 1.47 μm wavelength region is described. Using a traditional tapered microfiber-microsphere coupling method, multimode and single-mode lasing around the wavelength of 1.47 μm is observed using an 802 nm laser diode as a pump source. This Tm3+-Ho3+ codoped tellurite glass microsphere laser can be used in near-infrared telecommunications, biomedical, and astrophysical applications.