Acquired reversible Brown syndrome caused by focal abscess of the superior oblique muscle

Julius T Oatts; Jefferson J Doyle; Mary-Magdalene U Dodd; Iason S Mantagos; Linda R Dagi

doi:10.1016/j.jaapos.2018.12.003

Acquired reversible Brown syndrome caused by focal abscess of the superior oblique muscle

J AAPOS. 2019 Jun;23(3):172-174. doi: 10.1016/j.jaapos.2018.12.003. Epub 2019 Jan 30.

Authors

Julius T Oatts¹, Jefferson J Doyle², Mary-Magdalene U Dodd³, Iason S Mantagos⁴, Linda R Dagi⁴

Affiliations

¹ Department of Ophthalmology, University of California, San Francisco, California. Electronic address: [email protected].
² Department of Ophthalmology, Wilmer Eye Institute, Johns Hopkins University, Baltimore, Maryland.
³ Department of Ophthalmology, Alberta Childrens Hospital, Calgary, Alberta, Canada.
⁴ Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.

PMID: 30710645
DOI: 10.1016/j.jaapos.2018.12.003

Abstract

A 16-year-old boy with a history of relapsed acute myeloid leukemia and a right lower lobe lung abscess confirmed to be Aspergillus presented for a baseline eye examination prior to consideration of bone marrow transplantation. He noted double vision in up-and-left gaze, and his examination was consistent with an acquired right-sided Brown syndrome. Magnetic resonance imaging revealed a 4 mm rim-enhancing inflammatory focus in the right superior oblique muscle. His Brown syndrome resolved after treatment with systemic antimicrobials.

Publication types

Case Reports

MeSH terms

Abscess / complications*
Abscess / diagnosis
Abscess / microbiology
Adolescent
Aspergillosis / complications*
Aspergillosis / diagnosis
Aspergillosis / microbiology
Aspergillus / isolation & purification
Eye Infections, Fungal / complications*
Eye Infections, Fungal / diagnosis
Humans
Magnetic Resonance Imaging
Male
Ocular Motility Disorders / diagnosis
Ocular Motility Disorders / etiology*
Oculomotor Muscles / pathology*
Syndrome