Na2TiSiO5 is investigated as a novel anode of the lithium ion battery for the first time. The low working potential (above 0.1 V) and high capacity (>300 mA h g-1) give this material a high energy density, along with improved safety. After 100 cycles, the capacity retention remains at 94%. Furthermore, possible Li+-occupied sites and the migration path in the Na2TiSiO5 structure are also calculated and discussed in this work.