Importance of the DNA repair enzyme O6-alkyl guanine alkyltransferase (AT) in cancer chemotherapy

Cancer Treat Rev. 1988 Dec;15(4):279-92. doi: 10.1016/0305-7372(88)90026-6.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Alkylating Agents / pharmacology*
  • Animals
  • Antineoplastic Agents / pharmacology*
  • DNA Repair*
  • Humans
  • Methyltransferases / metabolism*
  • Neoplasms / drug therapy*
  • Neoplasms / enzymology
  • Nitrosourea Compounds / pharmacology*
  • O(6)-Methylguanine-DNA Methyltransferase
  • Species Specificity

Substances

  • Alkylating Agents
  • Antineoplastic Agents
  • Nitrosourea Compounds
  • Methyltransferases
  • O(6)-Methylguanine-DNA Methyltransferase