Feasibility of Image Fusion for Concurrent MRI Evaluation of Vessel Lumen and Vascular Calcifications in Peripheral Arterial Disease

AJR Am J Roentgenol. 2019 Apr;212(4):914-918. doi: 10.2214/AJR.18.20000. Epub 2019 Feb 4.

Abstract

Objective: With MR angiography of peripheral arterial disease, calcifications are unapparent, so a separate calcification-sensitive pulse sequence (proton density-weighted in-phase 3D stack-of-stars [PDIP-SOS]) is needed for complete assessment. We hypothesized that, despite being acquired separately, MR angiography and PDIP-SOS images could be coregistered and fused without loss of significant diagnostic information.

Conclusion: In a prospective study of 15 patients, MR image fusion enabled the simultaneous display of vessel lumen and vascular calcifications similarly to CT angiography.

Keywords: CT angiography; MR angiography; image fusion; unenhanced; vascular calcifications.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Aged
  • Aged, 80 and over
  • Computed Tomography Angiography / methods*
  • Contrast Media
  • Feasibility Studies
  • Female
  • Humans
  • Image Enhancement / methods*
  • Image Interpretation, Computer-Assisted
  • Imaging, Three-Dimensional
  • Iohexol
  • Magnetic Resonance Angiography / methods*
  • Male
  • Middle Aged
  • Peripheral Arterial Disease / diagnostic imaging*
  • Prospective Studies
  • Vascular Calcification / diagnostic imaging*

Substances

  • Contrast Media
  • Iohexol