Inhibition of 'jumping genes' promotes healthy ageing

Nature. 2019 Feb;566(7742):46-48. doi: 10.1038/d41586-018-07553-0.

Abstract

DNA sequences called retrotransposons can copy themselves and reintegrate at new sites in the genome, causing damage. It now seems that inhibiting this process can prevent age-related health decline in mice.

Keywords: Ageing; Molecular biology; Physiology.

Publication types

  • News
  • Comment

MeSH terms

  • Healthy Aging*
  • Humans
  • Inflammation
  • Interspersed Repetitive Sequences