Current Knowledge, Barriers to Implementation, and Future Directions in Palliative Care for End-Stage Liver Disease

Liver Transpl. 2019 May;25(5):787-796. doi: 10.1002/lt.25434. Epub 2019 Apr 5.

Abstract

End-stage liver disease (ESLD) is associated with a high degree of morbidity and mortality as well as symptom burden. Despite this, the rate of consultation with palliative care (PC) providers remains low, and invasive procedures near the end of life are commonplace. Studies show that involvement of PC providers improves patient satisfaction, and evidence from other chronic diseases demonstrates reduced costs of care and potentially increased survival. Better integration of PC is imperative but hindered by patient and provider misconceptions about its role in the care of patients with ESLD, specifically among candidates for liver transplantation. Additionally, reimbursement barriers and lack of provider knowledge may contribute to PC underutilization. In this review, we discuss the benefits of PC in ESLD, the variability of its delivery, and key stakeholders' perceptions about its use. Additionally, we identify barriers to more widespread PC adoption and highlight areas for future research.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Cost of Illness*
  • End Stage Liver Disease / diagnosis
  • End Stage Liver Disease / economics
  • End Stage Liver Disease / mortality
  • End Stage Liver Disease / therapy*
  • Health Plan Implementation / economics
  • Health Plan Implementation / organization & administration*
  • Health Plan Implementation / trends
  • Humans
  • Liver Transplantation
  • Palliative Care / economics
  • Palliative Care / organization & administration*
  • Palliative Care / trends
  • Patient Satisfaction
  • Quality of Life
  • Reimbursement Mechanisms / economics
  • Reimbursement Mechanisms / organization & administration
  • Reimbursement Mechanisms / trends
  • Severity of Illness Index
  • Stakeholder Participation
  • Waiting Lists