Spontaneous bilateral osteonecrosis of the mandible in a bisphosphonate-naive patient

A W Sklavos; S N Delpachitra; A M Thomas; A Nastri

doi:10.1016/j.bjoms.2019.01.015

Spontaneous bilateral osteonecrosis of the mandible in a bisphosphonate-naive patient

Br J Oral Maxillofac Surg. 2019 Apr;57(3):271-274. doi: 10.1016/j.bjoms.2019.01.015. Epub 2019 Feb 14.

Authors

A W Sklavos¹, S N Delpachitra², A M Thomas², A Nastri²

Affiliations

¹ The Royal Dental Hospital of Melbourne, Carlton, Victoria, Australia. Electronic address: [email protected].
² Royal Melbourne Hospital, Parkville, Victoria, Australia.

PMID: 30773304
DOI: 10.1016/j.bjoms.2019.01.015

Abstract

Medication-related osteonecrosis of the jaw is a well-described, yet poorly understood disease of bone that is commonly associated with antiresorptive and antiangiogenic drugs. We report a case of spontaneous bilateral osteonecrosis of the mandible in a patient with no previous exposure to either.

Keywords: MRONJ; ONJ; medication-related osteonecrosis of the jaw; oral pathology; osteonecrosis.

Publication types

Case Reports

MeSH terms

Angiogenesis Inhibitors
Bisphosphonate-Associated Osteonecrosis of the Jaw
Bone Density Conservation Agents
Diphosphonates
Humans
Mandible
Osteonecrosis*

Substances

Angiogenesis Inhibitors
Bone Density Conservation Agents
Diphosphonates