Subtourniquet pressures generated by application of wide-rubber tourniquets in standing, sedated horses

Vet Surg. 2019 Apr;48(3):417-423. doi: 10.1111/vsu.13181. Epub 2019 Feb 17.

Abstract

Objective: To determine the influence of location and movement on subtourniquet pressure (STP) generated by application of a wide-rubber tourniquet (WRT) on equine limbs.

Study design: Randomized experimental cross-over design.

Animals: Six standing, sedated horses.

Methods: Horses were sedated with detomidine hydrochloride (0.2 μg/kg IV), and 4 investigators applied WRTs to the antebrachium (AB), gaskin (GK), and midmetacarpus (MC) of each horse in a predetermined, randomized order. Subtourniquet pressure was consequently measured at 10-minute intervals (T0, T10, T20, T30) for 30 minutes. Indirect systolic blood pressure (SBP) was measured presedation, postsedation, and throughout the tourniquet application period. Target STP was established as SBP + 100 mm Hg. Limb movements at each location were classified as none, low, moderate, or high, on the basis of counts and magnitude.

Results: Mean STP did not change with time (P = .93) and exceeded SBP by 163 mm Hg (95% CI 122-205), 185 mm Hg (95% CI 156-214), and 402 mm Hg (95% CI 351-454) at the AB, GK, and MC, respectively. Mean STP at each location exceeded the target STP in 59 of 70 (81%) of the trials. Limb movements affected STP generated by tourniquets at the AB (P = .04) and MC (P < .0001) but not at the GK (P = .67).

Conclusion: Wide-rubber tourniquets applied at the AB, GK, and MC generated STP >100 mm Hg above SBP for 30 minutes in standing, sedated horses.

Clinical significance: Wide-rubber tourniquets as applied in this study can achieve and maintain the current recommended STP (SBP + 100 mm Hg) for equine IV regional limb perfusion. Number and magnitude of limb movement can decrease STP over time, potentially reducing the efficacy of a WRT.

Publication types

  • Clinical Trial, Veterinary

MeSH terms

  • Animals
  • Blood Pressure
  • Conscious Sedation
  • Cross-Over Studies
  • Female
  • Horses*
  • Hypnotics and Sedatives / pharmacology
  • Imidazoles / administration & dosage
  • Imidazoles / pharmacology
  • Male
  • Perfusion / veterinary
  • Pressure*
  • Random Allocation
  • Rubber
  • Tourniquets / veterinary*
  • Vascular Surgical Procedures

Substances

  • Hypnotics and Sedatives
  • Imidazoles
  • detomidine
  • Rubber