Background and aim: Studies of associations between various cancers and the ABO blood groups have shown elevated relative risks for some categories of disease. There has so far been no report of an evaluation of the relationship between the ABO blood groups and acne vulgaris. To investigate this association, we conducted a retrospective study of acne vulgaris diagnosed in Turkey.
Material and methods: All cases were clinically confirmed. Blood information was obtained on 498 individuals with acne vulgaris, and the distribution of ABO and Rh blood type for cases was compared with that of 419 healthy blood donors from the same geographic area.
Results: Patients with group A and B blood groups ratios were higher than the control group, but not statistically significant (P = 0.325 and P = 0.138). The ratio of the patient group with AB blood group was significantly higher than in the control group (P < 0.01). The ratio of blood group O of patient group was significantly lower than in the control group (P < 0.01). There were no statistically significant differences between the patient and control groups in the distribution of Rh factor.
Conclusion: Our study showed a significant association of AB and O blood groups with acne vulgaris. Further studies in a larger series on blood group antigens are needed to shed some light on the relationship between these antigens and skin cancer.
ملخص البحث : تهدف هذه الدراسة إلى تقصي الارتباط بين فصائل الدم وحالات حب الشباب. قام الباحثون بإجراء دراسة استرجاعية لحالات حب الشباب المؤكدة بإحدى المناطق بتركيا على 143 مريضاً وفصائل الدم ABO و Rhesus مقارنة مع 914 حالة من الأصحاء. أثبتت الدراسة أن نسبة المرضى بفصيلتي A and B كانت أعلى إحصائيا مقارنة مع مجموعة الأصحاء. أما نسبة فصيلة الدم (0) فكانت أقل إحصائيا في مجموعة الأصحاء. ولم توجد فروق إحصائية بين المرضى والأصحاء بالنسبة لفصيلة الدم (RH). وخلصت الدراسة إلى أن هناك فروق إحصائية بين فصائل الدم (ABO) وحالات حب الشباب.
Keywords: Acne vulgaris; blood; groups.