Mycobacterium chimaera Pulmonary Disease in Cystic Fibrosis Patients, France, 2010-2017

Emerg Infect Dis. 2019 Mar;25(3):611-613. doi: 10.3201/eid2503.181590.

Abstract

We report Mycobacterium chimaera pulmonary disease in 4 patients given a diagnosis of cystic fibrosis in a university hospital in Montpellier, France. All patients had M. chimaera-positive expectorated sputum specimens, clinical symptoms of pulmonary exacerbation, or a decrease in spirometry test results that improved after specific treatment.

Keywords: France; Mycobacterium avium complex; Mycobacterium chimaera; NTM; bacteria; cystic fibrosis; forced expiratory volume; forced vital capacity; nontuberculosis mycobacteria; pulmonary disease; respiratory infections; tuberculosis and other mycobacteria.

Publication types

  • Historical Article
  • Letter

MeSH terms

  • Adolescent
  • Adult
  • Antitubercular Agents / therapeutic use
  • Child
  • Cystic Fibrosis / complications*
  • Cystic Fibrosis / epidemiology*
  • Cystic Fibrosis / history
  • Disease Susceptibility
  • Female
  • France / epidemiology
  • History, 21st Century
  • Humans
  • Male
  • Mycobacterium avium Complex* / classification
  • Mycobacterium avium Complex* / drug effects
  • Mycobacterium avium Complex* / genetics
  • Mycobacterium avium-intracellulare Infection / diagnosis
  • Mycobacterium avium-intracellulare Infection / epidemiology*
  • Mycobacterium avium-intracellulare Infection / etiology*
  • Mycobacterium avium-intracellulare Infection / history
  • Public Health Surveillance
  • Respiratory Function Tests
  • Young Adult

Substances

  • Antitubercular Agents