Keywords: CyBorD, cyclophosphamide, bortezomib, and dexamethasone; POEMS syndrome; POEMS, polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes; SDH, spontaneous subdural hemorrhage; VEGF, vascular endothelial growth factor; and skin changes; autologous stem cell transplantation; chemotherapy; endocrinopathy; monoclonal gammopathy; polyneuropathy organomegaly.