Medallion-like dermal dendrocyte hamartoma: A rare congenital CD34-positive dermal lesion clinically and pathologically overlapping with fibroblastic connective tissue nevus

Pediatr Dermatol. 2019 May;36(3):397-399. doi: 10.1111/pde.13766. Epub 2019 Feb 27.

Abstract

Both medallion-like dermal dendrocyte hamartoma and fibroblastic connective tissue nevus are rare benign dermal lesions composed of CD34-positive spindle cells. Although regarded as different diseases, it is sometimes difficult to distinguish between them due to their clinical and pathological similarities. We present a case of medallion-like dermal dendrocyte hamartoma that could also be diagnosed as fibroblastic connective tissue nevus and propose the possibility of overlap in these diseases.

Keywords: CD34; congenital skin lesion; dermatofibrosarcoma protuberans; fibroblastic connective tissue nevus; medallion-like dermal dendrocyte hamartoma.

Publication types

  • Case Reports

MeSH terms

  • Antigens, CD34
  • Child
  • Diagnosis, Differential
  • Female
  • Hamartoma / congenital*
  • Hamartoma / diagnosis*
  • Humans
  • Nevus / diagnosis*
  • Skin Diseases / congenital*
  • Skin Diseases / diagnosis*

Substances

  • Antigens, CD34

Supplementary concepts

  • Connective Tissue Nevus