Impaired control of multiple viral infections in a family with complete IRF9 deficiency

J Allergy Clin Immunol. 2019 Jul;144(1):309-312.e10. doi: 10.1016/j.jaci.2019.02.019. Epub 2019 Feb 28.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cell Line
  • Child
  • Child, Preschool
  • Chlorocebus aethiops
  • Dogs
  • Family
  • Female
  • Genetic Predisposition to Disease*
  • Humans
  • Infant
  • Infant, Newborn
  • Interferon-Stimulated Gene Factor 3, gamma Subunit / deficiency*
  • Interferon-Stimulated Gene Factor 3, gamma Subunit / genetics
  • Leukocytes, Mononuclear / immunology
  • Macrophages / immunology
  • Male
  • Mutation
  • Primary Immunodeficiency Diseases / genetics*
  • Primary Immunodeficiency Diseases / immunology
  • Virus Diseases / genetics*
  • Virus Diseases / immunology

Substances

  • IRF9 protein, human
  • Interferon-Stimulated Gene Factor 3, gamma Subunit