Postmortem late phase histopathology after pulmonary vein isolation using a cryoballoon: A case report

Pacing Clin Electrophysiol. 2019 Jul;42(7):1066-1068. doi: 10.1111/pace.13643. Epub 2019 Mar 12.

Abstract

We report the autopsy case of 68-year-old woman who received cryoballoon (CB) ablation for paroxysmal atrial fibrillation 7 months before death. Both macroscopic and microscopic findings revealed no thrombus formation around pulmonary veins. Previous experimental studies have shown the lower risk of thrombus formation in CB ablation as compared to radiofrequency ablation. Our findings in the human autopsy case may support this merit of CB ablation. To confirm this benefit of CB ablation, further studies regarding histopathology of CB ablation should be performed.

Keywords: atrial fibrillation; cryoballoon; histopathology; pulmonary vein isolation.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Atrial Fibrillation / surgery*
  • Autopsy
  • Balloon Occlusion / methods*
  • Cryosurgery / methods*
  • Echocardiography
  • Electrocardiography
  • Fatal Outcome
  • Female
  • Humans
  • Pulmonary Veins / surgery*