Left Ventricular Mass and Thickness: Why Does It Matter?

Heart Fail Clin. 2019 Apr;15(2):159-166. doi: 10.1016/j.hfc.2018.12.013. Epub 2019 Feb 10.

Abstract

Several left ventricular geometric patterns have been described both in healthy and pathologic hearts. Left ventricular mass, wall thickness, and the ratio of wall thickness to radius are important measures to characterize the spectrum of left ventricular geometry. For clinicians, an increase in left ventricular mass is the hallmark of left ventricular hypertrophy. Although pathologic hypertrophy initially can be compensatory, eventually it may become maladaptive and evolve toward progressive left ventricular dysfunction and heart failure. In particular, patients who show left ventricular dilation and hypertrophy in association with a low relative wall thickness are likely to carry the highest risk.

Keywords: Heart failure; Hypertrophy; Left ventricular mass; Ventricular dysfunction.

Publication types

  • Review

MeSH terms

  • Echocardiography / methods*
  • Heart Failure / physiopathology*
  • Heart Ventricles / diagnostic imaging*
  • Heart Ventricles / physiopathology
  • Humans
  • Hypertrophy, Left Ventricular / physiopathology*
  • Ventricular Dysfunction, Left / physiopathology*