Biotransformation of 5-hydroxymethylfurfural by Acinetobacter oleivorans S27 for the synthesis of furan derivatives

Bioresour Technol. 2019 Jun:282:88-93. doi: 10.1016/j.biortech.2019.02.125. Epub 2019 Mar 1.

Abstract

Hydroxymethylfurfural (HMF) is an industrially important chemical which is a starting material in the production of plenty of platform chemicals. In this study, a complete biotransformation of HMF was achieved using a novel isolate, Acinetobacter oleivorans S27. This strain could tolerate up to 3000 mg/L of HMF concentration and convert to other furan derivatives. The conversion products includes high-value chemicals like 5-hydroxymethyl-2-furancarboxylic acid (HMFCA), a known interleukin inhibitor and 2,5-furan dicarboxylic acid (FDCA), an alternate of terephthalic acid in polyester industries. The biotransformation efficiency was found to be 100%, as there is complete conversion of HMF to other chemicals. Most importantly, it is an environmental friendly process for the production of furan derivatives.

Keywords: 2,5-Furan dicarboxylic acid; 5-Hydroxymethyl 2-furancarboxylic acid; 5-Hydroxymethyl furfural; Acinetobacter oleivorans S27; Response Surface Methodology.

Publication types

  • Retracted Publication

MeSH terms

  • Acinetobacter / metabolism*
  • Biotransformation
  • Furaldehyde / analogs & derivatives*
  • Furaldehyde / metabolism
  • Furans / metabolism*

Substances

  • Furans
  • 5-hydroxymethylfurfural
  • Furaldehyde