CXCL12 Derived From Endothelial Cells Promotes Atherosclerosis to Drive Coronary Artery Disease

Circulation. 2019 Mar 5;139(10):1338-1340. doi: 10.1161/CIRCULATIONAHA.118.037953.
No abstract available

Keywords: atherosclerosis; chemokines; coronary artery disease; genome-wide association studies; inflammation.

Publication types

  • Letter
  • Meta-Analysis
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Chemokine CXCL12 / deficiency
  • Chemokine CXCL12 / genetics
  • Chemokine CXCL12 / metabolism*
  • Coronary Artery Disease / genetics
  • Coronary Artery Disease / metabolism*
  • Coronary Artery Disease / pathology
  • Disease Models, Animal
  • Disease Progression
  • Endothelial Cells / metabolism*
  • Endothelial Cells / pathology
  • Genetic Predisposition to Disease
  • Genome-Wide Association Study
  • Humans
  • Mice, Knockout, ApoE
  • Phenotype
  • Plaque, Atherosclerotic*
  • Polymorphism, Single Nucleotide
  • Risk Factors

Substances

  • CXCL12 protein, human
  • Chemokine CXCL12
  • Cxcl12 protein, mouse