Impact of summer heat on mortality and years of life lost: Application of a novel indicator of daily excess hourly heat

Background: Previous studies have widely assessed heat-mortality relationships across global regions, while the epidemiological evidence regarding the heat effect on years of life lost (YLL) is relatively sparse. Current investigations using daily mean data cannot take hourly temperature variation into consideration and may underestimate heat effects. We developed a novel indicator, daily excess hourly heat (DEHH), to precisely evaluate the potential heat effects on mortality and YLL.

Methods: Hourly data on temperature and daily information, including concentrations of air pollutants, relative humidity, and records of all registered deaths were obtained in Wuhan, China during the warm seasons (May-September) of 2009-2012. DEHH, developed in this study, is defined as daily total hourly temperatures that exceed a specific heat threshold. By performing time series regression analyses, we assessed the changes in daily mortality and YLL per interquartile range (IQR) increase in DEHH across different lag days.

Results: The heat threshold evaluated by the Akaike Information Criterion for DEHH calculation is 30 °C (92th percentile of whole-year mean temperature distribution). Daily average DEHH was 13.9 °C, with an IQR of 19.9 °C. Linear exposure-response curves were found between DEHH and two health outcomes. Generally, heat effects lasted for 2-3 days and DEHH at lag 0-1 was most strongly associated with increased mortality and YLL. The effects were especially remarkable for stroke and ischemic heart disease mortality. Most intense effect on YLL was found in non-accidental deaths (20.11, 95% confidence interval: 8.90-31.33) at lag 0-1. More DEHH-related mortality and YLL from cardiovascular deaths were observed among males. People aged 0-74 years and males suffered more from YLL burden due to high temperatures.

Conclusions: Our study demonstrated that DEHH may be an alternative indicator to precisely measure heat effects on daily mortality and YLL. Further DEHH-based evidence from large scale investigations is needed so as to better understand heat-associated health burden and improve public response to extremely high temperatures.