Abstract
We report the sharp reduction in the incidence of AIDS defining cancers in a multicentric, retrospective study carried out since 1991 and involving six Infectious Diseases Units spread across Italy. However, due to the parallel increase in non-AIDS defining cancers, cancer incidence was not reduced. Focusing on predictors of death in HIV-positive patients with neoplastic disease, multivariate models revealed that males as well as drug abusers were independently associated with a poor clinical outcome.
MeSH terms
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Acquired Immunodeficiency Syndrome / complications*
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Adult
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Analysis of Variance
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Anus Neoplasms / epidemiology
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Carcinoma, Hepatocellular / epidemiology
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Case-Control Studies
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Central Nervous System Neoplasms / epidemiology
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Female
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HIV Infections / complications
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HIV Long-Term Survivors
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Humans
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Incidence
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Italy / epidemiology
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Leukemia / epidemiology
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Liver Neoplasms / epidemiology
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Lymphoma / epidemiology
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Lymphoma, Non-Hodgkin / epidemiology
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Middle Aged
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Neoplasms / epidemiology*
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Prevalence
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Retrospective Studies
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Sarcoma, Kaposi / epidemiology
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Sex Factors
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Substance-Related Disorders
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Uterine Cervical Neoplasms / epidemiology