Identification of a novel allele, HLA-DPB1*417:01:02, in an African American deceased donor

HLA. 2019 Jul;94(1):88. doi: 10.1111/tan.13526. Epub 2019 Mar 27.

Authors

Jeremy B Sherrill¹, Nezih Cereb², Chak-Sum Ho¹

Affiliations

¹ Histocompatibility Laboratory, Gift of Life Michigan, Ann Arbor, Michigan.
² Histocompatibility Laboratory, HistoGenetics LLC, Ossining, New York.

PMID: 30884171
DOI: 10.1111/tan.13526

Abstract

HLA-DPB1*417:01:02 differs from HLA-DPB1*417:01:01 by a synonymous nucleotide substitution at codon 43.

Keywords: Linkage Biosciences LinkSeq; Pacific Biosciences single molecule real-time DNA sequencing; new allele.

© 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

MeSH terms

Alleles
Amino Acid Substitution
Base Sequence
Black or African American / genetics*
Codon*
HLA-DP beta-Chains / genetics*
Histocompatibility Testing / methods*
Humans
Polymorphism, Single Nucleotide*
Sequence Analysis, DNA / methods*
Sequence Homology
Tissue Donors

Substances

Codon
HLA-DP beta-Chains
HLA-DPB1 antigen