Objective: To investigate the safety and influencing factors of ct-guided percutaneous lung biopsy in pneumoconiosis patients. Methods: The data of 63 patients with pneumoconiosis who underwent ct-guided percutaneous lung biopsy in our hospital were studied to analyze the incidence of complications and influencing factors of percutaneous lung biopsy. Results: 63 cases of pneumoconiosis patients received CT guided percutaneous lung biopsy. There were 29 cases of complications (46.03%) , including 20 pneumothorax (37.75%) , 12 bleeding (19.05%) , and 3 cases of liquid pneumothorax (4.76%) . The single factor chi square analysis showed that there were significant differences in age, depth of focus, puncture position and puncture times (P<0.05) , and there was significant difference between the occurrence of hemorrhage and age, type of focus, size of focus, and the location of puncture site (P<0.05) . The unconditional LogisticL multiple factor regression analysis showed that the depth of the lesion was an independent risk factor for concurrency pneumothorax, and the size of the lesion was an independent risk factor for bleeding. Conclusion: Complications of CT-guided percutaneous pulmonary biopsy are mainly pneumothorax and hemorrhage. Age, focus type, focus size, focus depth, puncture site, and puncture times are all the factors of complications.
目的: 探讨CT引导下经皮肺穿刺活检术在尘肺患者中应用的安全性及其影响因素。 方法: 对2015年1月至2017年1月至湖南省职业病防治院进行CT引导下经皮肺穿刺活检术的63例尘肺病患者资料进行研究,分析患者在CT引导下经皮肺穿刺活检术后并发病发生的影响因素。用SPSS 18.0软件进行统计分析,定性资料用构成比进行描述;定量资料用x±s描述;各组间比较采用χ(2)检验;并发症的影响因素分析采用非条件logistic回归分析。 结果: 63例尘肺患者接受CT引导下经皮肺穿刺活检术后,共有29例出现并发症(46.03%),其中气胸20例(37.75%)、出血12例(19.05%)、液气胸3例(4.76%)。经χ(2)检验显示,不同年龄、病灶深度、穿刺体位、穿刺次数组间出现气胸的差异均有统计学意义(P<0.05);不同年龄、病灶类型、病灶大小、穿刺部位组间出血的发生差异均有统计学意义(P<0.05)。非条件logistic多因素回归分析结果显示,病灶深度为并发气胸的独立危险因素(OR=6.964,95%CI:1.850~26.219),病灶过小为并发出血的独立危险因素(OR=0.043,95%CI:0.004~0.442)。 结论: 尘肺患者CT引导下的经皮肺穿刺活检术并发症主要为气胸和出血,年龄、病灶类型、病灶大小、病灶深度、穿刺部位、穿刺次数等均为并发症出现的影响因素。.
Keywords: CT guided; Complications; Influence factor; Percutaneous lung biopsy; Pneumoconiosis.