Sentinel lymph node mapping in endometrial and cervical cancer: a survey of practices and attitudes in gynecologic oncologists

J Gynecol Oncol. 2019 May;30(3):e35. doi: 10.3802/jgo.2019.30.e35.

Abstract

Objective: To determine patterns among gynecologic oncologists in sentinel lymph node mapping (SLNM) for endometrial cancer (EC) and cervical cancer (CC).

Methods: A online survey assessing the practice of SLNM, including incidence, patterns of usage, and reasons for non-use was distributed to Society of Gynecologic Oncology candidate and full members in August 2017. Descriptive statistics and univariate analysis was performed.

Results: The 1,117 members were surveyed and 198 responses (17.7%) were received. Of the 70% (n=139) performing SLNM, the majority reported use for both CC and EC (64.0%) or EC alone (33.1%). In those using SLNM in EC, the majority (86.6%) performed SLNM in >50% of cases for all patients (56.3%), International Federation of Gynecology and Obstetrics grade 1 (43.0%) and 2 (42.2%). Reported benefits of SLNM in EC were reduced surgical morbidity (89.6%), lymphedema (85.2%), and operative time (63.7%). Among those using SLNM for CC, the majority (73.1%) did so in >50% of cases. In EC, 77.2% and 21.3% reported that micro-metastatic disease (0.2-2.0 cm) and isolated tumor cells (ITCs) should be treated as node positive, respectively. In those not using SLNM for EC (n=64) and CC (n=105), concerns were regarding efficacy of SLNM and lack of training. When queried regarding training, 73.7% felt that SLNM would impact skill in full lymphadenectomy (LND).

Conclusion: The SLNM is utilized frequently among gynecologic oncologists for EC and CC staging. Common reasons for non-uptake include uncertainty of current data, lack of training and technology. Concerns exist regarding impact of SLNM in fellowship training of LND.

Keywords: Cervical Cancer; Endometrial Cancer; Lymphadenectomy; Sentinel Lymph Node.

MeSH terms

  • Adult
  • Aged
  • Attitude of Health Personnel*
  • Endometrial Neoplasms / epidemiology
  • Endometrial Neoplasms / pathology*
  • Female
  • Gynecology / statistics & numerical data
  • Gynecology / trends
  • Humans
  • Lymph Node Excision / methods
  • Lymph Node Excision / statistics & numerical data
  • Lymphatic Metastasis
  • Male
  • Middle Aged
  • Neoplasm Staging
  • Oncologists / statistics & numerical data
  • Oncologists / trends
  • Practice Patterns, Physicians'* / statistics & numerical data
  • Practice Patterns, Physicians'* / trends
  • Sentinel Lymph Node / pathology*
  • Sentinel Lymph Node Biopsy* / methods
  • Sentinel Lymph Node Biopsy* / psychology
  • Sentinel Lymph Node Biopsy* / statistics & numerical data
  • Surveys and Questionnaires
  • United States / epidemiology
  • Uterine Cervical Neoplasms / epidemiology
  • Uterine Cervical Neoplasms / pathology*