Optimal Strategies for the Diagnosis of Acute Pulmonary Embolism: A Health Technology Assessment [Internet]

Sections

• External Reviewers
• Authorship
• Acknowledgements
• Abbreviations
• Protocol Amendments
• Executive Summary
• Rationale and Policy Issues
• Policy Question
• Objectives
• Research Questions
• Methods
• Patient Perspectives and Experiences
• Implementation Issues
• Environmental Impact
• Ethics
• Discussion
• References
• Appendix 1. Literature Search Strategy
• Appendix 2. Supplemental Search Strategy
• Appendix 3. Clinical Full-Text Screening Checklist
• Appendix 4. Clinical Data Extraction Form for Primary Studies
• Appendix 5. Clinical Data Extraction Form for Systematic Reviews
• Appendix 6. Pulmonary Embolism Diagnosis and Management Strategies and Subsequent Outcomes
• Appendix 7. Selection Criteria for Network Meta-Analysis
• Appendix 8. Study Selection Flowchart (PRISMA) for Clinical Review
• Appendix 9. Overlap Among Primary Studies from Included Systematic Reviews
• Appendix 10. List of Excluded Studies for Clinical Review (Questions 1, 2, and 3)
• Appendix 11. Quality Assessment Questions for Clinical Review
• Appendix 12. Characteristics of Included Systematic Reviews for Clinical Review of Risk Stratification (Question 1)
• Appendix 13. Diagnostic Accuracy Outcomes Reported by Included Systematic Review (Question 1)
• Appendix 14. Utility Outcomes Reported by Included Systematic Reviews (Question 1)
• Appendix 15. Summary of Quality or Risk of Bias Assessments Conducted by Included Systematic Reviews for Clinical Review (Question 1)
• Appendix 16. Characteristics of Included Primary Studies for Clinical Review (Questions 2 and 3)
• Appendix 17. Quality Assessment of Included Primary Studies for Clinical Review (Questions 2 and 3)
• Appendix 18. Individual Study Diagnostic Test Accuracy Data (Questions 2 and 3)
• Appendix 19. Individual Study Utility and Safety Data (Questions 2 and 3)
• Appendix 20. Study Characteristics of Studies in Pregnant Patients
• Appendix 21. Results of individual studies reporting stratified results and multiple imaging conditions
• Appendix 22. Statistical Appendix (Questions 2 and 3)
• Appendix 23. Risk Stratification: Parameters for the Economic Evaluation
• Appendix 24. Characteristics of existing published economic evaluation on diagnosis of PE
• Appendix 25. Diagnostic Pathway
• Appendix 26. List of Diagnostic Strategies Considered in the Economic Model
• Appendix 27. Detailed Results of the Reference Case
• Appendix 28. Additional Sensitivity Analysis Results
• Appendix 29. Selection of Studies on Patient Perspectives and Experience
• Appendix 30. Study Characteristics Table
• Appendix 31. Critical Appraisal of Included Publications
• Appendix 32. CADTH Survey Questions
• Appendix 33. Survey Respondents – Self Identified Description
• Appendix 34. Study Characteristics Table
• Appendix 35. Selection of Studies on Environmental Impact
• Appendix 36. Selection of Studies on Ethics Analysis
• Appendix 37. Characteristics of Included Ethics Reports