Abstract
Two patients with prolactinomas who could not tolerate a large dose of bromocriptine were treated with combination of bromocriptine and tamoxifen. This combined therapy normalized the PRL level and restored a regular ovulatory cycle, which resulted in pregnancy.
MeSH terms
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Adult
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Animals
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Bromocriptine / therapeutic use*
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Callitrichinae
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Drug Therapy, Combination
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Female
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Follicle Stimulating Hormone / blood
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Humans
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Pituitary Neoplasms / drug therapy*
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Pituitary Neoplasms / metabolism
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Pituitary Neoplasms / physiopathology
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Pregnancy
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Pregnancy Complications, Neoplastic / drug therapy*
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Prolactin / blood
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Prolactin / metabolism*
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Rabbits
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Rats
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Tamoxifen / therapeutic use*
Substances
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Tamoxifen
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Bromocriptine
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Prolactin
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Follicle Stimulating Hormone