2018 TSOC guideline focused update on diagnosis and treatment of pulmonary arterial hypertension

Wei-Chun Huang; Chih-Hsin Hsu; Shih-Hsien Sung; Wan-Jing Ho; Chun-Yuan Chu; Chih-Ping Chang; Yu-Wei Chiu; Chun-Hsien Wu; Wei-Ting Chang; Lin Lin; Shoa-Lin Lin; Chin-Chang Cheng; Yih-Jer Wu; Shu-Hao Wu; Tsu-Yi Hsieh; Hsao-Hsun Hsu; Morgan Fu; Zen-Kong Dai; Ping-Hung Kuo; Juey-Jen Hwang; Shu-Meng Cheng; TSOC pulmonary hypertension committee

doi:10.1016/j.jfma.2018.12.009

2018 TSOC guideline focused update on diagnosis and treatment of pulmonary arterial hypertension

J Formos Med Assoc. 2019 Dec;118(12):1584-1609. doi: 10.1016/j.jfma.2018.12.009. Epub 2019 Mar 26.

Authors

Wei-Chun Huang¹, Chih-Hsin Hsu², Shih-Hsien Sung³, Wan-Jing Ho⁴, Chun-Yuan Chu⁵, Chih-Ping Chang⁶, Yu-Wei Chiu⁷, Chun-Hsien Wu⁸, Wei-Ting Chang⁹, Lin Lin¹⁰, Shoa-Lin Lin¹¹, Chin-Chang Cheng¹², Yih-Jer Wu¹³, Shu-Hao Wu¹⁴, Tsu-Yi Hsieh¹⁵, Hsao-Hsun Hsu¹⁶, Morgan Fu¹⁷, Zen-Kong Dai⁵, Ping-Hung Kuo¹⁸, Juey-Jen Hwang¹⁹, Shu-Meng Cheng²⁰; TSOC pulmonary hypertension committee

Affiliations

¹ Department of Critical Care Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan; School of Medicine, National Yang-Ming University, Taipei, Taiwan; Department of Physical Therapy, Fooyin University, Kaohsiung, Taiwan.
² Department of Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan.
³ School of Medicine, National Yang-Ming University, Taipei, Taiwan; Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
⁴ Department of Internal Medicine, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan.
⁵ Division of Cardiology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
⁶ Division of Cardiology, China Medical University Hospital, Taichung, Taiwan.
⁷ Department of Internal Medicine, Far Eastern Memorial Hospital, New Taipei City, Taiwan.
⁸ Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
⁹ Division of Cardiovascular Medicine, Chi-Mei Medical Center, Tainan City, Taiwan.
¹⁰ Cardiovascular Center, National Taiwan University Hospital, Hsinchu Branch, Hsinchu, Taiwan.
¹¹ Department of Internal Medicine, Yuan's General Hospital, Kaohsiung, Taiwan.
¹² Department of Critical Care Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan; School of Medicine, National Yang-Ming University, Taipei, Taiwan; Department of Physical Therapy, Fooyin University, Kaohsiung, Taiwan; Pulmonary Hypertension Center, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
¹³ Department of Medicine, Mackay Medical College, New Taipei City, Taiwan; Pulmonary Hypertension Interventional Medicine, Cardiovascular Center, Mackay Memorial Hospital, Taipei City, Taiwan.
¹⁴ Pulmonary Hypertension Interventional Medicine, Cardiovascular Center, Mackay Memorial Hospital, Taipei City, Taiwan.
¹⁵ Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.
¹⁶ Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan.
¹⁷ Department of Internal Medicine, Chang Gung Memorial Hospital, Kaohsiung, Taiwan.
¹⁸ Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
¹⁹ Cardiovascular Division, Department of Internal Medicine, National Taiwan University College of Medicine and Hospital, Taipei, Taiwan; National Taiwan University Hospital Yunlin Branch, Douliu City, Taiwan. Electronic address: [email protected].
²⁰ Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan. Electronic address: [email protected].

PMID: 30926248
DOI: 10.1016/j.jfma.2018.12.009

Abstract

Pulmonary arterial hypertension (PAH) is characterized as a progressive and sustained increase in pulmonary vascular resistance, which may induce right ventricular failure. In 2014, the Working Group on Pulmonary Hypertension of the Taiwan Society of Cardiology (TSOC) conducted a review of data and developed a guideline for the management of PAH.⁴ In recent years, several advancements in diagnosis and treatment of PAH has occurred. Therefore, the Working Group on Pulmonary Hypertension of TSOC decided to come up with a focused update that addresses clinically important advances in PAH diagnosis and treatment. This 2018 focused update deals with: (1) the role of echocardiography in PAH; (2) new diagnostic algorithm for the evaluation of PAH; (3) comprehensive prognostic evaluation and risk assessment; (4) treatment goals and follow-up strategy; (5) updated PAH targeted therapy; (6) combination therapy and goal-orientated therapy; (7) updated treatment for PAH associated with congenital heart disease; (8) updated treatment for PAH associated with connective tissue disease; and (9) updated treatment for chronic thromboembolic pulmonary hypertension.

Keywords: Guideline; Pulmonary arterial hypertension; Pulmonary hypertension.

MeSH terms

Cardiology
Humans
Practice Guidelines as Topic*
Pulmonary Arterial Hypertension / diagnosis*
Pulmonary Arterial Hypertension / therapy*
Societies, Medical
Taiwan