Genome Sequencing of Polydrug-, Multidrug-, and Extensively Drug-Resistant Mycobacterium tuberculosis Strains from South India

Sivakumar Shanmugam; Narender Kumar; Dina Nair; Mohan Natrajan; Srikanth Prasad Tripathy; Sharon J Peacock; Soumya Swaminathan; Uma Devi Ranganathan

doi:10.1128/MRA.01388-18

Genome Sequencing of Polydrug-, Multidrug-, and Extensively Drug-Resistant Mycobacterium tuberculosis Strains from South India

Microbiol Resour Announc. 2019 Mar 21;8(12):e01388-18. doi: 10.1128/MRA.01388-18.

Authors

Sivakumar Shanmugam¹, Narender Kumar², Dina Nair¹, Mohan Natrajan¹, Srikanth Prasad Tripathy¹, Sharon J Peacock^{2

3}, Soumya Swaminathan⁴, Uma Devi Ranganathan⁵

Affiliations

¹ ICMR-National Institute for Research in Tuberculosis, Chennai, India.
² Department of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.
³ London School of Hygiene and Tropical Medicine, London, United Kingdom.
⁴ World Health Organization, Geneva, Switzerland.
⁵ ICMR-National Institute for Research in Tuberculosis, Chennai, India [email protected].

Abstract

The genomes of 16 clinical Mycobacterium tuberculosis isolates were subjected to whole-genome sequencing to identify mutations related to resistance to one or more anti-Mycobacterium drugs. The sequence data will help in understanding the genomic characteristics of M. tuberculosis isolates and their resistance mutations prevalent in South India.

Abstract

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