Objective: To evaluate impact of 24-h proteinuria level in preeclampsia on maternal/perinatal outcomes.
Methods: Singleton pregnancies with preeclampsia delivered after 24 weeks of gestation were included. Patients were divided into mild (0.3 to <2 g) (n=72), severe (2 to <5 g) (n=30), and massive (≥5 g) (n=24) proteinuria groups, and cut-off values of 24-h proteinuria for composite adverse maternal and neonatal outcomes were calculated.
Results: Twenty-four hour proteinuria level cut-offs for composite adverse outcomes were 3275 mg (72.2% sensitivity, 85.6% specificity) and 2395 mg (72.7% sensitivity, 78% specificity) respectively.
Conclusion: Severe and massive proteinuria were related to poor maternal, perinatal, and neonatal outcomes.
Keywords: Pregnancy; preeclampsia; proteinuria.