The phosphatase UBASH3B/Sts-1 is a negative regulator of Bcr-Abl kinase activity and leukemogenesis

Leukemia. 2019 Sep;33(9):2319-2323. doi: 10.1038/s41375-019-0468-y. Epub 2019 Apr 8.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Carcinogenesis / genetics*
  • Cell Line
  • Fusion Proteins, bcr-abl / genetics*
  • HEK293 Cells
  • Humans
  • Imatinib Mesylate / pharmacology
  • Mice
  • Phosphoric Monoester Hydrolases / genetics*
  • Phosphorylation / drug effects
  • Phosphorylation / genetics
  • Protein Tyrosine Phosphatases / genetics*

Substances

  • Imatinib Mesylate
  • Fusion Proteins, bcr-abl
  • Phosphoric Monoester Hydrolases
  • Protein Tyrosine Phosphatases
  • UBASH3B protein, human