Generalized hypertrichosis due to secukinumab in a patient with moderate psoriasis: A case of serendipity or zemblanity?

Dermatol Ther. 2019 May;32(3):e12894. doi: 10.1111/dth.12894. Epub 2019 Apr 17.

Abstract

After 4 months of therapy with secukinumab, a 67-year-old man with moderate psoriasis developed generalized hypertrichosis, along with PASI 90. The patient denied any drug intake, apart from secukinumab, nor applications of any creams. Moreover, this event did not really bother the patient, thus the therapy was not discontinued and the hypertrichosis is persisting as psoriasis' control.

Keywords: alopecia areata; anti-IL17; drug adverse events; hypertrichosis; psoriasis.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Aged
  • Alopecia Areata / chemically induced
  • Antibodies, Monoclonal, Humanized / adverse effects*
  • Humans
  • Hypertrichosis / chemically induced*
  • Male
  • Psoriasis / drug therapy*

Substances

  • Antibodies, Monoclonal, Humanized
  • secukinumab