Impact of atrial septal defect closure on diffusing capacity for nitric oxide and carbon monoxide

Martina Nassif; Reindert P van Steenwijk; Ivo van der Lee; Peter J Sterk; Frans H C de Jongh; Jacqueline M Hogenhout; Jan G P Tijssen; Barbara J M Mulder; Robbert J de Winter

doi:10.1183/23120541.00260-2018

Impact of atrial septal defect closure on diffusing capacity for nitric oxide and carbon monoxide

ERJ Open Res. 2019 Apr 8;5(2):00260-2018. doi: 10.1183/23120541.00260-2018. eCollection 2019 Apr.

Authors

Martina Nassif¹, Reindert P van Steenwijk², Ivo van der Lee³, Peter J Sterk², Frans H C de Jongh⁴, Jacqueline M Hogenhout², Jan G P Tijssen¹, Barbara J M Mulder^{1

5}, Robbert J de Winter¹

Affiliations

¹ Dept of Cardiology, Amsterdam UMC - University of Amsterdam, Amsterdam, The Netherlands.
² Dept of Respiratory Medicine, Amsterdam UMC - University of Amsterdam, Amsterdam, The Netherlands.
³ Dept of Pulmonology, Spaarne Hospital, Hoofddorp, The Netherlands.
⁴ Dept of Pulmonology, Medisch Spectrum Twente, Enschede, The Netherlands.
⁵ Netherlands Heart Institute, Utrecht, The Netherlands.

Abstract

Atrial septal defects are characterised by a low D _LNO /D _LCOc ratio in diffusion testing. Successful percutaneous closure shows an increase in D _LNO /D _LCOc ratio and vital capacity through correction of a hyperdynamic pulmonary circulation. http://ow.ly/Rqkc30o5yMM.