Photooxygenation of 2-propargylfurans: a path to structurally diverse nitrogen-containing 5-membered rings

Chem Commun (Camb). 2019 May 7;55(38):5443-5446. doi: 10.1039/c9cc01197h.

Abstract

The photooxygenation of 2-propargylfurans enabled access to original nitrogen-containing cyclopentenones and related compounds in a one-pot fashion. By employing readily-available substrates such as furans and amines, we succeeded in achieving a high degree of molecular complexity. Relying on the introduction of an alkyne moiety and tailored substrates, this transformation reveals a new facet for reaction sequences featuring the photooxygenation of furans.