Nipah Virus Sequences from Humans and Bats during Nipah Outbreak, Kerala, India, 2018

Emerg Infect Dis. 2019 May;25(5):1003-1006. doi: 10.3201/eid2505.181076.

Abstract

We retrieved Nipah virus (NiV) sequences from 4 human and 3 fruit bat (Pteropus medius) samples from a 2018 outbreak in Kerala, India. Phylogenetic analysis demonstrated that NiV from humans was 96.15% similar to a Bangladesh strain but 99.7%-100% similar to virus from Pteropus spp. bats, indicating bats were the source of the outbreak.

Keywords: Human; India; Kerala; Nipah virus; Pteropus medius; next-generation sequencing; qRT-PCR; viruses.

Publication types

  • Historical Article
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cells, Cultured
  • Chiroptera / virology*
  • Cytopathogenic Effect, Viral
  • Disease Outbreaks*
  • Henipavirus Infections / epidemiology*
  • Henipavirus Infections / history
  • Henipavirus Infections / transmission
  • Henipavirus Infections / virology*
  • History, 21st Century
  • Humans
  • India / epidemiology
  • Mutation
  • Nipah Virus / classification*
  • Nipah Virus / genetics*
  • Public Health Surveillance