We investigated a cluster of Mycobacterium fortuitum and M. goodii prosthetic joint surgical site infections occurring during 2010-2014. Cases were defined as culture-positive nontuberculous mycobacteria surgical site infections that had occurred within 1 year of joint replacement surgery performed on or after October 1, 2010. We identified 9 cases by case finding, chart review, interviews, surgical observations, matched case-control study, pulsed-field gel electrophoresis of isolates, and environmental investigation; 6 cases were diagnosed >90 days after surgery. Cases were associated with a surgical instrument vendor representative being in the operating room during surgery; other potential sources were ruled out. A tenth case occurred during 2016. This cluster of infections associated with a vendor reinforces that all personnel entering the operating suite should follow infection control guidelines; samples for mycobacterial culture should be collected early; and postoperative surveillance for <90 days can miss surgical site infections caused by slow-growing organisms requiring specialized cultures, like mycobacteria.
Keywords: Mycobacterium fortuitum; Mycobacterium goodii; National Healthcare Safety Network; Oregon; USA; arthroplasty; bacteria; case–control studies; environment; hair; hip joint; humans; infection control; knee joint; nontuberculous mycobacteria; prostheses and implants; pulsed-field gel electrophoresis; replacement; soil; surgical wound infection; tuberculosis and other mycobacteria; water.