Feasibility of stereotactic radiotherapy using a 1.5 T MR-linac: Multi-fraction treatment of pelvic lymph node oligometastases

Anita M Werensteijn-Honingh; Petra S Kroon; Dennis Winkel; Ellart M Aalbers; Bram van Asselen; Gijsbert H Bol; Kevin J Brown; Wietse S C Eppinga; Corine A van Es; Markus Glitzner; Eline N de Groot-van Breugel; Sara L Hackett; Martijn Intven; Jan G M Kok; Charis Kontaxis; Alexis N Kotte; Jan J W Lagendijk; Mariëlle E P Philippens; Rob H N Tijssen; Jochem W H Wolthaus; Simon J Woodings; Bas W Raaymakers; Ina M Jürgenliemk-Schulz

doi:10.1016/j.radonc.2019.01.024

Feasibility of stereotactic radiotherapy using a 1.5 T MR-linac: Multi-fraction treatment of pelvic lymph node oligometastases

Radiother Oncol. 2019 May:134:50-54. doi: 10.1016/j.radonc.2019.01.024. Epub 2019 Feb 1.

Authors

Anita M Werensteijn-Honingh¹, Petra S Kroon², Dennis Winkel², Ellart M Aalbers², Bram van Asselen², Gijsbert H Bol², Kevin J Brown³, Wietse S C Eppinga², Corine A van Es², Markus Glitzner², Eline N de Groot-van Breugel², Sara L Hackett², Martijn Intven², Jan G M Kok², Charis Kontaxis², Alexis N Kotte², Jan J W Lagendijk², Mariëlle E P Philippens², Rob H N Tijssen², Jochem W H Wolthaus², Simon J Woodings², Bas W Raaymakers², Ina M Jürgenliemk-Schulz²

Affiliations

¹ University Medical Center Utrecht, Department of Radiotherapy, 3508 GA Utrecht, The Netherlands. Electronic address: [email protected].
² University Medical Center Utrecht, Department of Radiotherapy, 3508 GA Utrecht, The Netherlands.
³ Elekta AB, SE-103 93 Stockholm, Sweden.

PMID: 31005224
DOI: 10.1016/j.radonc.2019.01.024

Abstract

Online adaptive radiotherapy using the 1.5 Tesla MR-linac is feasible for SBRT (5 × 7 Gy) of pelvic lymph node oligometastases. The workflow allows full online planning based on daily anatomy. Session duration is less than 60 min. Quality assurance tests, including independent 3D dose calculations and film measurements were passed.

Keywords: MR-guided radiotherapy; MR-linac; Magnetic resonance imaging; Radiotherapy; Workflow.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Feasibility Studies
Humans
Lymph Nodes / diagnostic imaging
Lymph Nodes / pathology
Lymph Nodes / radiation effects*
Lymphatic Metastasis
Magnetic Resonance Imaging / methods
Male
Particle Accelerators
Positron-Emission Tomography / methods
Prostatic Neoplasms / diagnostic imaging
Prostatic Neoplasms / pathology
Prostatic Neoplasms / radiotherapy*
Radiosurgery / instrumentation*
Radiosurgery / methods
Radiotherapy Dosage
Radiotherapy, Image-Guided / methods