1 Division of Hematology, Departments of Medicine, Laboratory Medicine and Pathobiology, Institute of Health Policy Management and Evaluation, University of Toronto, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario, Canada.
2 Department of Anesthesia, St. Michael's Hospital, 30 Bond Street, Toronto, Ontario, Canada.
3 Departments of Anesthesia and Physiology and Li Ka Shing Knowledge Institute of St. Michael's Hospital, University of Toronto, St. Michael's Hospital, 30 Bond Street, Toronto, Ontario, Canada.