[Oncogenes, their implications in cell growth, differentiation and carcinogenesis]

Gan To Kagaku Ryoho. 1987 Feb;14(2):363-72.
[Article in Japanese]

Abstract

Cancer Research has changed substantially over the past several years since oncogenes were isolated from cancer cells. More than 40 oncogenes have been identified to date from tumor viruses and cancer cells. Many of the gene products seem related to signalling pathways that determine growth and differentiation of cells. This review attempts to summarize much of the currently available data and to gain future perspectives.

Publication types

  • English Abstract
  • Review

MeSH terms

  • 9,10-Dimethyl-1,2-benzanthracene
  • Animals
  • Carcinogens*
  • Cell Transformation, Neoplastic
  • Cell Transformation, Viral
  • Epidermal Growth Factor / genetics
  • Genes, Viral
  • Humans
  • Mammary Neoplasms, Experimental / chemically induced
  • Mammary Neoplasms, Experimental / genetics
  • Neoplasms / etiology*
  • Neoplasms / pathology
  • Platelet-Derived Growth Factor / genetics
  • Retroviridae / genetics
  • Transfection
  • Urinary Bladder Neoplasms / genetics

Substances

  • Carcinogens
  • Platelet-Derived Growth Factor
  • 9,10-Dimethyl-1,2-benzanthracene
  • Epidermal Growth Factor