Bergeyella cardium: Clinical Characteristics and Draft Genome of an Emerging Pathogen in Native and Prosthetic Valve Endocarditis

Jennifer S Mulliken; Charles Langelier; Jehan Z Budak; Steve Miller; David Dynerman; Samantha Hao; Lucy M Li; Emily Crawford; Amy Lyden; Michael H Woodworth; Joseph L DeRisi; Edward Desmond; Christina Browne; Araceli Luu; Donald J Grandis; William Grossman; Tobias Deuse; Gregory P Melcher

doi:10.1093/ofid/ofz134

Bergeyella cardium: Clinical Characteristics and Draft Genome of an Emerging Pathogen in Native and Prosthetic Valve Endocarditis

Open Forum Infect Dis. 2019 Mar 15;6(4):ofz134. doi: 10.1093/ofid/ofz134. eCollection 2019 Apr.

Authors

Jennifer S Mulliken¹, Charles Langelier^{1

2}, Jehan Z Budak¹, Steve Miller³, David Dynerman², Samantha Hao², Lucy M Li², Emily Crawford^{2

4}, Amy Lyden², Michael H Woodworth⁵, Joseph L DeRisi^{2

6}, Edward Desmond⁷, Christina Browne⁷, Araceli Luu⁷, Donald J Grandis⁸, William Grossman⁸, Tobias Deuse⁹, Gregory P Melcher¹

Affiliations

¹ Division of Infectious Diseases, University of California, San Francisco.
² Chan Zuckerberg Biohub, San Francisco.
³ Department of Laboratory Medicine, University of California, San Francisco.
⁴ Department of Microbiology and Immunology, University of California, San Francisco.
⁵ Division of Infectious Diseases, Emory University, Atlanta, Georgia.
⁶ Biochemistry and Biophysics, University of California, San Francisco.
⁷ California Department of Public Health, Microbial Diseases Laboratory, Richmond.
⁸ Division of Cardiology, University of California, San Francisco.
⁹ Division of Adult Cardiothoracic Surgery, University of California, San Francisco.

Abstract

Bergeyella cardium is a new species in the family Flavobacteriaceae that was recently described in 3 cases of native valve infective endocarditis. We report the first case of B. cardium prosthetic valve endocarditis, provide the first draft genome of this species, and review the microbiologic characteristics of this emerging pathogen.

Abstract

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