Management of thin endometrium in assisted reproduction: a clinical practice guideline from the Canadian Fertility and Andrology Society

Reprod Biomed Online. 2019 Jul;39(1):49-62. doi: 10.1016/j.rbmo.2019.02.013. Epub 2019 Mar 20.

Abstract

The impact and management of thin endometrium is a common challenge for patients undergoing assisted reproduction. The objective of this Canadian Fertility and Andrology Society (CFAS) guideline is to provide evidence-based recommendations using the GRADE (Grading of Recommendations, Assessment, Development and Evaluations) framework on the assessment, impact and management of thin endometrium in assisted reproduction. The effect of endometrial thickness on pregnancy and live birth outcomes in ovarian stimulation and IVF (fresh and frozen cycles) is addressed. In addition, recommendations on the use of adjuvants to improve endometrial thickness and pregnancy outcomes are provided.

Keywords: Adjuvants; Assisted Reproduction; Endometrium.

Publication types

  • Practice Guideline
  • Review

MeSH terms

  • Andrology / organization & administration
  • Andrology / standards
  • Canada
  • Endometrium / pathology*
  • Female
  • Fertility / physiology
  • Humans
  • Organ Size
  • Pregnancy
  • Pregnancy Outcome
  • Reproductive Medicine / organization & administration
  • Reproductive Medicine / standards
  • Reproductive Techniques, Assisted / standards*
  • Societies, Medical / standards
  • Uterine Diseases / diagnosis
  • Uterine Diseases / pathology
  • Uterine Diseases / therapy*