Results of free flap reconstruction for patients aged 80 years or older with head and neck cancer

Auris Nasus Larynx. 2020 Feb;47(1):123-127. doi: 10.1016/j.anl.2019.04.005. Epub 2019 May 3.

Abstract

Objective: Free flap reconstruction in elderly patients is one of the most challenging surgeries in the treatment of head and neck cancers. The aim of this study was to examine the oncological and functional outcomes of free flap reconstruction for elderly patients with head and neck cancer.

Methods: We retrospectively reviewed elderly patients who underwent free flap reconstruction for the treatment of head and neck cancers. All patients were 80 years or older. Clinicopathologic features, surgical procedures, oncological and functional outcomes were obtained from medical records.

Results: Free flap reconstructions were performed in 13 patients (3 female, 10 male). The mean age was 82.6 ± 3.4 years (range: 80-91). The mean follow-up period was 23.3 months (range 4-41 months). The mean disease-free survival was 49 ± 6 months (range 4-60 months). All patients had been alive more than one year after surgery. Reconstruction was performed using free jejunum in 10 patients and radial forearm flap in 3 patients. Graft necrosis occurred in 2 patients. Other two patients experienced major postoperative medical complications.

Conclusion: Free flap reconstruction in well-selected older adults is safe and effective. Advanced age should not preclude consideration of free flap reconstruction in those patients.

Keywords: ASA physical status classifications; Elderly; Forearm flap; Free jejunum; Hypopharyngeal cancer; Oral cancer.

MeSH terms

  • Aged, 80 and over
  • Disease-Free Survival
  • Female
  • Forearm*
  • Free Tissue Flaps*
  • Gastrointestinal Hemorrhage / epidemiology
  • Head and Neck Neoplasms / pathology
  • Head and Neck Neoplasms / surgery
  • Humans
  • Hypopharyngeal Neoplasms / pathology
  • Hypopharyngeal Neoplasms / surgery*
  • Hypopharynx / surgery
  • Jejunum / transplantation*
  • Length of Stay
  • Male
  • Mesenteric Artery, Superior
  • Mesenteric Vascular Occlusion / epidemiology
  • Mouth / surgery
  • Mouth Neoplasms / pathology
  • Mouth Neoplasms / surgery*
  • Plastic Surgery Procedures / methods*
  • Postoperative Complications / epidemiology*
  • Retrospective Studies
  • Squamous Cell Carcinoma of Head and Neck / pathology
  • Squamous Cell Carcinoma of Head and Neck / surgery*
  • Tissue Transplantation / methods